Skip to Content
Find More Like This
Return to Search

Restoration of normal phenotype in cancer cells

United States Patent

December 8, 1998
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying .beta..sub.1 integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Human breast epithelial cells were shown to be particularly responsive.
Bissell; Mina J. (Berkeley, CA), Weaver; Valerie M. (Oakland, CA)
The Regents of the University of California (Oakland, CA)
08/ 726,230
October 4, 1996
This invention was made with U.S. Government support under Contract No. DE-AC03-76SF00098 between the U.S. Department of Energy and the University of California for the operation of Lawrence Berkeley Laboratory. The U.S. Government may have certain rights in this invention.