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Host cells and methods for producing diacid compounds

United States Patent

April 24, 2018
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention provides for a method of producing one or more fatty acid derived dicarboxylic acids in a genetically modified host cell which does not naturally produce the one or more derived fatty acid derived dicarboxylic acids. The invention provides for the biosynthesis of dicarboxylic acid ranging in length from C3 to C26. The host cell can be further modified to increase fatty acid production or export of the desired fatty acid derived compound, and/or decrease fatty acid storage or metabolism.
Steen; Eric J. (San Francisco, CA), Fortman; Jeffrey L. (San Francisco, CA), Dietrich; Jeffrey A. (San Francisco, CA), Keasling; Jay D. (Berkeley, CA)
The Regents of the University of California (Oakland, CA)
13/ 900,397
May 22, 2013
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT The invention described and claimed herein was made utilizing funds supplied by the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. The government has certain rights in this invention.