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Producing alpha-olefins using polyketide synthases

United States Patent

January 2, 2018
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention provides for a polyketide synthase (PKS) capable of synthesizing an .alpha.-olefin, such as 1-hexene or butadiene. The present invention also provides for a host cell comprising the PKS and when cultured produces the .alpha.-olefin.
Fortman; Jeffrey L. (San Francisco, CA), Katz; Leonard (Oakland, CA), Steen; Eric J. (Berkeley, CA), Keasling; Jay D (Berkeley, CA)
The Regents of the University of California (Oakland, CA)
14/ 853,821
September 14, 2015
STATEMENT OF GOVERNMENTAL SUPPORT This invention was made with government support under Contract No. DE-AC02-05CH11231 awarded by the U.S. Department of Energy and Award No. 0540879 awarded by the National Science Foundation. The government has certain rights in the invention