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Transcription activator-like effectors

United States Patent

November 22, 2016
View the Complete Patent at the US Patent & Trademark Office
Provided herein are compositions, kits and methods useful in the construction of designer transcription activator-like effector (dTALE) polypeptides.
Zhang; Feng (Cambridge, MA), Cong; Le (Brookline, MA), Kosuri; Sriram (Cambridge, MA), Church; George M. (Brookline, MA)
President and Fellows of Harvard College (Cambridge, MA)
13/ 353,662
January 19, 2012
GOVERNMENT SUPPORT This invention was made with Government Support under NS073124, HG003170, and HG005550 awarded by the National Institutes of Health, under EEC-0540879 awarded by the National Science Foundation, under W911NF-08-1-0254 awarded by U.S. Department of Defense/DARPA, and under DE-FG02-02ER63445 awarded by the U.S. Department of Energy. The Government has certain rights in the invention.