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Compositions and methods for increased ethanol titer from biomass

United States Patent

November 15, 2016
View the Complete Patent at the US Patent & Trademark Office
The present application discloses the identification of novel I. orientalis ADH1, ADHa, and ADHb genes, and the production and characterization of genetically modified yeast cells in which these genes were altered. Provided herein are isolated I. orientalis ADH1, ADHa, and ADHb polynucleotides and polypeptides, genetically modified yeast cells that overexpress I. orientalis ADH1 and/or contain deletions or disruptions of ADHa and/or ADHb, and methods of using culturing these modified cells to produce ethanol.
Jessen; Holly J. (Chanhassen, MN), Yi; Jian (Carlsbad, CA)
Cargill, Incorporated (Wayzata, MN)
13/ 988,899
November 22, 2011
GOVERNMENT INTEREST This invention was made with governmental support under contract number DE-FC36-07 GO17055 awarded by the United States of America Department of Energy. The United States of America Government has certain rights in the invention.