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Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry

United States Patent

November 8, 2016
View the Complete Patent at the US Patent & Trademark Office
Nanopost Arrays Anchor Molecules, Improve Ion Yields for Laser Mass Spectrometry
The production and use of semiconducting nanopost arrays made by nanofabrication is described herein. These nanopost arrays (NAPA) provide improved laser ionization yields and controllable fragmentation with switching or modulation capabilities for mass spectrometric detection and identification of samples deposited on them.
Vertes; Akos (Reston, VA), Walker; Bennett N. (Washington, DC), Stolee; Jessica A. (Washington, DC), Retterer; Scott T. (Knoxville, TN)
The George Washington University (Washington, DC)
12/ 755,769
April 7, 2010
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This invention was made with government support under grant number DEFG02-01ER15129 from the Department of Energy. The U.S. Government has certain rights in this invention.