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Recombinant clostridia that fix CO.sub.2 and CO and uses thereof

United States Patent

June 24, 2014
View the Complete Patent at the US Patent & Trademark Office
The present invention relates a recombinant Clostridium expressing one or more heterologous Wood-Ljungdahl (WL) genes. In particular, the recombinant Clostridium produces a metabolite at an increased level. The present invention also relates to a method for producing a metabolite by the recombinant Clostridium.
Papoutsakis; Eleftherios T. (Newark, DE), Al-Hinai; Mohab Ali (Newark, DE), Jones; Shawn William (Newark, DE), Indurthi; Dinesh Chanukya (Newark, DE), Mitchell; Daniel Knox (Newark, DE), Fast; Alan (Newark, DE)
University of Delaware (Newark, DE)
13/ 229,033
September 9, 2011
REFERENCE TO U.S. GOVERNMENT SUPPORT This work is supported by a grant from the U.S. Advanced Research Projects Agency--Energy (ARPA-E) of Department of Energy (DOE) (Award No. 5710002809). The United States has certain rights in the invention.