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Alteration and modulation of protein activity by varying post-translational modification

United States Patent

March 3, 2015
View the Complete Patent at the US Patent & Trademark Office
Idaho National Laboratory - Visit the Technology Transfer and Commercialization Office Website
Thermoacidophilic derived enzymes for biomass conversion to fuels and chemicals
Embodiments of the invention include methods of altering the enzymatic activity or solubility of an extremophilic enzyme or post-translationally modifying a protein of interest via using isolated or partially purified glycosyltransferases and/or post-translational modification proteins, extracts of cells comprising glycosyltransferases and/or post-translational modification proteins, and/or in cells comprising one or more glycosyltransferases and/or post-translational modification proteins.
Thompson; David N. (Idaho Falls, ID), Reed; David W. (Idaho Falls, ID), Thompson; Vicki S. (Idaho Falls, ID), Lacey; Jeffrey A. (Idaho Falls, ID), Apel; William A. (Jackson, WY)
Battelle Energy Alliance, LLC (Idaho Falls, ID)
12/ 655,993
January 12, 2010
GOVERNMENT RIGHTS This invention was made with government support under Contract Numbers DE-AC07-99ID13727 and DE-AC07-05ID14517 awarded by the United States Department of Energy. The government has certain rights in the invention.