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Genetically modified yeast species, and fermentation processes using genetically modified yeast

United States Patent

January 7, 2014
View the Complete Patent at the US Patent & Trademark Office
Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications include deletion of non-specific or specific aldose reductase gene(s), deletion of xylitol dehydrogenase gene(s) and/or overexpression of xylulokinase.
Rajgarhia; Vineet (Kingsport, TN), Koivuranta; Kari (Helsinki, FI), Penttila; Merja (Helsinki, FI), Ilmen; Marja (Helsinki, FI), Suominen; Pirkko (Maple Grove, MN), Aristidou; Aristos (Maple Grove, MN), Miller; Christopher Kenneth (Cottage Grove, MN), Olson; Stacey (St. Bonifacius, MN), Ruohonen; Laura (Helsinki, FI)
Cargill Incorporated (Wayzata, MN)
13/ 107,882
May 14, 2011
This invention was made under contract no. DE-FC07-021D14349 with the United States Department of Energy. The United States Government has certain rights to this invention.