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Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides

United States Patent

October 15, 2013
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention provides luminescent complexes between a lanthanide ion and an organic ligand which contains 1,2-hydroxypyridinone units. The complexes of the invention are stable in aqueous solutions and are useful as molecular probes, for example in medical diagnostics and bioanalytical assay systems. The invention also provides methods of using the complexes of the invention.
Raymond; Kenneth N. (Berkeley, CA), Xu; Jide (Berkeley, CA), Moore; Evan G. (Berkeley, CA), Werner; Eric J. (Berkeley, CA)
The Regents of the University of California (Oakland, CA)
12/ 373,275
July 10, 2007
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT This invention was made with government support under Grant Numbers HL069832 and DK057814 awarded by the National Institutes of Health and Contract Number DE-AC03-76SF00098 awarded by the Department of Energy. The government has certain rights in the invention.