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Rotanone analogs: method of preparation and use

United States Patent

October 8, 2013
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention provides rotenone analogs and methods of making and using them. Labeled with single photon and positron emitting isotopes, the rotenone analogs of the present invention are useful in, for example, clinical imaging applications as tracers to measure cardiac blood flow and detect regions of ischemia.
VanBrocklin; Henry F. (Walnut Creek, CA), O'Neil; James P. (San Leandro, CA), Gibbs; Andrew R. (Pleasant Hill, CA), Erathodiyil; Nandanan (Singapore, SG)
The Regents of the University of California (Oakland, CA)
12/ 273,509
November 18, 2008
STATEMENT OF GOVERNMENTAL SUPPORT This invention was made with government support under Grant (Contract) No. DE-AC03-76F00098 awarded by The United States Department of Energy and Grant No. 5R01EB000482-03 awarded by The United States Department of Health and Human Services. The government has certain rights to this invention.