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Producing biofuels using polyketide synthases

United States Patent

April 16, 2013
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention provides for a non-naturally occurring polyketide synthase (PKS) capable of synthesizing a carboxylic acid or a lactone, and a composition such that a carboxylic acid or lactone is included. The carboxylic acid or lactone, or derivative thereof, is useful as a biofuel. The present invention also provides for a recombinant nucleic acid or vector that encodes such a PKS, and host cells which also have such a recombinant nucleic acid or vector. The present invention also provides for a method of producing such carboxylic acids or lactones using such a PKS.
Katz; Leonard (Oakland, CA), Fortman; Jeffrey L (San Francisco, CA), Keasling; Jay D (Berkeley, CA)
The Regents of the University of California (Oakland, CA)
12/ 921,463
April 29, 2009
STATEMENT OF GOVERNMENTAL SUPPORT This invention was made with government support under Contract No. DE-AC02-05CH11231 awarded by the U.S. Department of Energy and under Award No. 0540879 awarded by the National Science Foundation. The government has certain rights in the invention.