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FGF growth factor analogs

United States Patent

July 24, 2012
View the Complete Patent at the US Patent & Trademark Office
Brookhaven National Laboratory - Visit the Office of Technology Commercialization and Partnerships Website
The present invention provides a fibroblast growth factor heparin-binding analog of the formula: ##STR00001## where R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, X, Y and Z are as defined, pharmaceutical compositions, coating compositions and medical devices including the fibroblast growth factor heparin-binding analog of the foregoing formula, and methods and uses thereof.
Zamora; Paul O. (Gaithersburg, MD), Pena; Louis A. (Poquott, NY), Lin; Xinhua (Plainview, NY), Takahashi; Kazuyuki (Germantown, MD)
BioSurface Engineering Technologies, Incle (Rockvile, MD), Brookhaven and Science Associates (Upton, NY)
11/ 361,565
February 23, 2006
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT The U.S. Government has a paid-up license in this invention and the right in limited circumstances to require the patent owner to license others on reasonable terms as provided for by the terms of Grant No. 1-R43-HL077039 awarded by the U.S. NHBLI, National Institutes of Health; Cooperative Research and Development Agreement (CRADA) between BioSurface Engineering Technologies, Inc. and Brookhaven Science Associates, LLC, operator of Brookhaven National Laboratory, No. BNL-C-03-01; and U.S. Department of Energy Contract No. DE-AC02-98CH10886.