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Method for forming polymerized microfluidic devices

United States Patent

November 1, 2011
View the Complete Patent at the US Patent & Trademark Office
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Microfluidic Devices
Methods for making a micofluidic device according to embodiments of the present invention include defining a cavity. Polymer precursor solution is positioned in the cavity, and exposed to light to begin the polymerization process and define a microchannel. In some embodiments, after the polymerization process is partially complete, a solvent rinse is performed, or fresh polymer precursor introduced into the microchannel. This may promote removal of unpolymerized material from the microchannel and enable smaller feature sizes. The polymer precursor solution may contain an iniferter. Polymerized features therefore may be capped with the iniferter, which is photoactive. The iniferter may aid later binding of a polyacrylamide gel to the microchannel surface.
Sommer; Gregory J. (Livermore, CA), Hatch; Anson V. (Tracy, CA), Wang; Ying-Chih (Pleasanton, CA), Singh; Anup K. (Danville, CA), Renzi; Ronald F. (Tracy, CA), Claudnic; Mark R. (Livermore, CA)
Sandia Corporation (Livermore, CA)
12/ 321,881
January 26, 2009
STATEMENT REGARDING RESEARCH & DEVELOPMENT The United States Government has a paid-up license in this invention and the right in limited circumstances to require the patent owner to license others on reasonable terms as provided for by the terms of contract No. DE-AC04-94AL85000 awarded by the U.S. Department of Energy to Sandia Corporation.