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Systems for the expression of orthogonal translation components in eubacterial host cells

United States Patent

June 14, 2011
View the Complete Patent at the US Patent & Trademark Office
The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions.
Ryu; Youngha (San Diego, CA), Schultz; Peter G. (La Jolla, CA)
The Scripps Research Institute (La Jolla, CA)
11/ 715,672
March 7, 2007
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT This invention was made with U.S. Government support under Contract No. ER46051 from the Department of Energy. The U.S. Government may have certain rights to the invention.