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Lateral flow devices

United States Patent

September 21, 2010
View the Complete Patent at the US Patent & Trademark Office
An analytical test for an analyte comprises (a) a base, having a reaction area and a visualization area, (b) a capture species, on the base in the visualization area, comprising nucleic acid, and (c) analysis chemistry reagents, on the base in the reaction area. The analysis chemistry reagents comprise (i) a substrate comprising nucleic acid and a first label, and (ii) a reactor comprising nucleic acid. The analysis chemistry reagents can react with a sample comprising the analyte and water, to produce a visualization species comprising nucleic acid and the first label, and the capture species can bind the visualization species.
Mazumdar; Debapriya (Urbana, IL), Liu; Juewen (Urbana, IL), Lu; Yi (Champaign, IL)
The Board of Trustees of the University of Illinois (Urbana, IL)
11/ 686,601
March 15, 2007
FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT The subject matter of this application may have been funded in part under the following research grants and contracts: Contract Numbers DMR-0117792 and CTS-0120978 awarded by the National Science Foundation, Contract Number DEFG02-01ER63179 awarded by United States Department of Energy, and Contract Number DAAD19-03-1-0227 awarded by the Department of Defense. The U.S. Government may certain have rights in this invention.