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Helical synthetic peptides that stimulate cellular cholesterol efflux

United States Patent

April 6, 2010
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention provides peptides comprising at least one amphipathic alpha helix and having an cholesterol mediating activity and a ABCA stabilization activity. The invention further provides methods of using such peptides.
Bielicki; John K. (Castro Valley, CA), Natarajan; Pradeep (Hacienda Heights, CA)
The Regents of the University of California (Oakland, CA)
11/ 014,187
December 15, 2004
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT This invention was made with Government support under Grant No. HL59483 awarded by the NIH/NCI to J. K. Bielicki and U.S. Department of Energy Contract No. DE-AC03-76SF00098. The Government has certain rights in this invention.