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Destabilized bioluminescent proteins

United States Patent

July 31, 2007
View the Complete Patent at the US Patent & Trademark Office
Purified nucleic acids, vectors and cells containing a gene cassette encoding at least one modified bioluminescent protein, wherein the modification includes the addition of a peptide sequence. The duration of bioluminescence emitted by the modified bioluminescent protein is shorter than the duration of bioluminescence emitted by an unmodified form of the bioluminescent protein.
Allen; Michael S. (Knoxville, TN), Rakesh; Gupta (New Delhi, IN), Gary; Sayler S. (Blaine, TN)
University of Tennessee Research Foundation (Knoxville, TN)
10/ 827,133
April 19, 2004
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This invention was made with U.S. government support under grant number ROI 2580 127 awarded by the Department of Energy. The U.S. government may have certain rights in the invention.