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Size separation of analytes using monomeric surfactants

United States Patent

April 12, 2005
View the Complete Patent at the US Patent & Trademark Office
Ames Laboratory - Visit the Iowa State University Research Foundation - Office of Intellectual Property & Technology Transfer Website
A sieving medium for use in the separation of analytes in a sample containing at least one such analyte comprises a monomeric non-ionic surfactant of the of the general formula, B-A, wherein A is a hydrophilic moiety and B is a hydrophobic moiety, present in a solvent at a concentration forming a self-assembled micelle configuration under selected conditions and having an aggregation number providing an equivalent weight capable of effecting the size separation of the sample solution so as to resolve a target analyte(s) in a solution containing the same, the size separation taking place in a chromatography or electrophoresis separation system.
Yeung; Edward S. (Ames, IA), Wei; Wei (Ames, IA)
Iowa State University Research Foundation, Inc. (Ames, IA)
10/ 085,656
February 27, 2002
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT This invention was made, in part, with Government support from the Department of Energy under Grant Number W-7405-ENG-82 and from the National Institutes of Health under Grant Number HG-01804. Therefore, the Government may have certain rights in this invention.