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Engineering disease resistance with pectate lyase-like genes

United States Patent

March 8, 2005
View the Complete Patent at the US Patent & Trademark Office
A mutant gene coding for pectate lyase and homologs thereof is provided, which when incorporated in transgenic plants effect an increased level disease resistance in such plants. Also is provided the polypeptide sequence for the pectate lyase of the present invention. Methods of obtaining the mutant gene, producing transgenic plants which include the nucleotide sequence for the mutant gene and producing improved disease resistance in a crop of such transgenic plants are also provided.
Vogel; John (Sunnyvale, CA), Somerville; Shauna (Portola Valley, CA)
Carnegie Institution of Washington (Washington, DC)
09/ 684,960
October 10, 2000
This invention relates to a mutant gene coding for pectate lyase and homologs thereof and the use of such mutant genes in producing transgenic plants having improved disease resistance. The invention described herein was made in the course of work under grant number DE-FG02-94ER20133 and grant number DE-FG02-97ER20133 from the U.S. Department of Energy and grant number F32 GM 19499 of the National Institute of Health. The U.S. government may retain certain rights in this invention.