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Passive injection control for microfluidic systems

United States Patent

December 21, 2004
View the Complete Patent at the US Patent & Trademark Office
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Microfluidic Devices
Apparatus for eliminating siphoning, "dead" regions, and fluid concentration gradients in microscale analytical devices. In its most basic embodiment, the present invention affords passive injection control for both electric field-driven and pressure-driven systems by providing additional fluid flow channels or auxiliary channels disposed on either side of a sample separation column. The auxiliary channels are sized such that volumetric fluid flow rate through these channels, while sufficient to move the sample away from the sample injection region in a timely fashion, is less than that through the sample separation channel or chromatograph.
Paul; Phillip H. (Livermore, CA), Arnold; Don W. (Livermore, CA), Neyer; David W. (Castro Valley, CA)
Sandia National Laboratories (Livermore, CA)
10/ 341,870
January 13, 2003
STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under contract no. DE-AC04-94AL85000 awarded by the U.S. Department of Energy to Sandia Corporation. The Government has certain rights in the invention.