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Sample preparation and detection device for infectious agents

United States Patent

June 10, 2003
View the Complete Patent at the US Patent & Trademark Office
Lawrence Livermore National Laboratory - Visit the Industrial Partnerships Office Website
A sample preparation and analysis device which incorporates both immunoassays and PCR assays in one compact, field-portable microchip. The device provides new capabilities in fluid and particle control which allows the building of a fluidic chip with no moving parts, thus decreasing fabrication cost and increasing the robustness of the device. The device can operate in a true continuous (not batch) mode. The device incorporates magnetohydrodynamic (MHD) pumps to move the fluid through the system, acoustic mixing and fractionation, dielectropheretic (DEP) sample concentration and purification, and on-chip optical detection capabilities.
Miles; Robin R. (Danville, CA), Wang; Amy W. (Oakland, CA), Fuller; Christopher K. (Livermore, CA), Lemoff; Asuncion V. (Union City, CA), Bettencourt; Kerry A. (Dublin, CA), Yu; June (Livermore, CA)
The Regents of the University of California (Oakland, CA)
09/ 815,624
March 23, 2001
The United States Government has rights in this invention pursuant to Contract No. W-7405-ENG-48 between the United States Department of Energy and the University of California for the operation of Lawrence Livermore National Laboratory.