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Production of amino acids using auxotrophic mutants of methylotrophic bacillus

United States Patent

July 17, 2001
View the Complete Patent at the US Patent & Trademark Office
A method of producing amino acids by culturing an amino acid auxotroph of a biologically pure strain of a type I methylotrophic bacterium of the genus Bacillus which exhibits sustained growth at C. using methanol as a carbon and energy source and requiring vitamin B.sub.12 and biotin is provided.
Hanson; Richard S. (Wayzata, MN), Flickinger; Michael C. (St. Paul, MN), Schendel; Frederick J. (Falcon Heights, MN), Guettler; Michael V. (Waconia, MN)
Regents of the University of Minnesota (Minneapolis, MN)
07/ 673,264
March 20, 1991
SUPPORT This invention was made with Government support under Contract Number DE-ACO2-82ER12029, awarded by the United States Department of Energy. The Government has certain rights in the invention.