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Method and apparatus for imaging a sample on a device

United States Patent

June 26, 2001
View the Complete Patent at the US Patent & Trademark Office
A method and apparatus for imaging a sample are provided. An electromagnetic radiation source generates excitation radiation which is sized by excitation optics to a line. The line is directed at a sample resting on a support and excites a plurality of regions on the sample. Collection optics collect response radiation reflected from the sample I and image the reflected radiation. A detector senses the reflected radiation and is positioned to permit discrimination between radiation reflected from a certain focal plane in the sample and certain other planes within the sample.
Trulson; Mark (Santa Clara, CA), Stern; David (Mountain View, CA), Fiekowsky; Peter (Los Altos, CA), Rava; Richard (Palo Alto, CA), Walton; Ian (Menlo Park, CA), Fodor; Stephen P. A. (Palo Alto, CA)
Affymetrix Technologies, N.V. (Curacao, AN)
09/ 348,216
July 6, 1999
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT This invention was made with Government support under grant nos. DE-FG03-92ER81275 (SBIR) awarded by the Department of Energy and/or H600813-1, -2 between Affymetrix, Inc. and the National Institutes of Health. The Government has certain rights in this invention.