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Method for determining properties of red blood cells

United States Patent

February 13, 2001
View the Complete Patent at the US Patent & Trademark Office
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A method for quantifying the concentration of hemoglobin in a cell, and indicia of anemia, comprises determining the wavelength of the longitudinal mode of a liquid in a laser microcavity; determining the wavelength of the fundamental transverse mode of a red blood cell in the liquid in the laser microcavity; and determining if the cell is anemic from the difference between the wavelength of the longitudinal mode and the fundamental transverse mode. In addition to measuring hemoglobin, the invention includes a method using intracavity laser spectroscopy to measure the change in spectra as a function of time for measuring the influx of water into a red blood cell and the cell's subsequent rupture.
Gourley; Paul L. (Albuquerque, NM)
Sandia Corporation (Albuquerque, NM)
09/ 221,331
December 23, 1998
STATEMENT OF GOVERNMENT INTEREST The United States Government has rights in this invention pursuant to Department of Energy Contract No. DE-AC0494AL85000 with Sandia Corporation.