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Microfabricated capillary array electrophoresis device and method

United States Patent

November 7, 2000
View the Complete Patent at the US Patent & Trademark Office
A capillary array electrophoresis (CAE) micro-plate with an array of separation channels connected to an array of sample reservoirs on the plate. The sample reservoirs are organized into one or more sample injectors. One or more waste reservoirs are provided to collect wastes from reservoirs in each of the sample injectors. Additionally, a cathode reservoir is also multiplexed with one or more separation channels. To complete the electrical path, an anode reservoir which is common to some or all separation channels is also provided on the micro-plate. Moreover, the channel layout keeps the distance from the anode to each of the cathodes approximately constant.
Simpson; Peter C. (Oakland, CA), Mathies; Richard A. (Moraga, CA), Woolley; Adam T. (Belmont, MA)
The Regents of The University of California (Berkeley, CA)
08/ 965,738
November 7, 1997
STATEMENT AS TO FEDERALLY SPONSORED RESEARCH This invention was made with Government support under Grant No. DE-FG-91ER61125, awarded by the U.S. Department of Energy, and Grant No. HG01399, awarded by the National Institutes of Health. The Government has certain rights in the invention.