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Apparatus and method for assaying electrophysiological effects

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Oak Ridge National Laboratory - Visit the Partnerships Directorate Website
A culture vessel for biological samples contains a plurality of individually addressable electrodes and a means of maintaining these electrodes at various potentials, whereby cells may be cultured in a wide variety of electric fields to rapidly assess the influence of field strength, frequency, or waveform on cell growth or inhibition, platelet adhesion, gene expression, or other responses of interest while maintaining an otherwise uniform culture environment for the cells. The electrode array may be formed on a rigid, reusable substrate or it may be disposable.
Lauf, Robert J. (Oak Ridge, TN)
10/ 017,511
December 14, 2001
[0001] This invention was made with United States Government support under Contract No. DE-AC05-00OR22725 awarded by the United States Department of Energy. The Government has certain rights in this invention.