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Modulation of cellular adhesion with lipid membrane micro-arrays

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
A method and device for controlled cell adhesion is provided. The device comprises lipid bilayer membranes arranged into discrete areas in a micro-array. They are useful for screening and modulation of living cell adhesion and growth on a solid substrate. The lipid bilayer membranes are doped with various lipids and/or proteins to modulate the adherence of the cells being used in the device.
Groves, John T. (Berkeley, CA), Mahal, Lara K. (New York City, NY), Bertozzi, Carolyn R. (Berkeley, CA)
10/ 076,727
February 13, 2002
[0002] This invention was made with U.S. Government support under Contract Number DE-AC03-76SF00098 between the U.S. Department of Energy and The Regents of the University of California for the management and operation of the Lawrence Berkeley National Laboratory. The U.S. Government has certain rights in this invention.