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United States Patent Application

View the Complete Application at the US Patent & Trademark Office
The invention provides a method of activating a silicone polymer surface using a laser, particularly an excimer laser, so that the silicone is more reactive. A silicone article containing an activated surface is also provided, and can be used to make silicone implants that can be securely fixed to tissue. One example is an implantable prosthesis to treat blindness caused by outer retinal degenerative diseases. The device bypasses damaged photoreceptors and electrically stimulates the undamaged neurons of the retina. Electrical stimulation is achieved using a silicone microelectrode array (MEA). A safe, protein adhesive is used in attaching the MEA to the retinal surface and assist in alleviating focal pressure effects.
Laude, Lucien (Rabastens-de-Bigorre, FR), Rowley, Adrian (Los Angeles, CA), Humayun, Mark (Glendale, CA), Weiland, James (Valencia, CA)
12/ 041,652
March 3, 2008
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT [0002] This application was made with government support under Grant Nos. DOE-(Artificial Retina program) and NSF-EEC-0310723 (BMES ERC), awarded by The United States Department Of Energy and the National Science Foundation, respectively. The government has certain rights in the invention.