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Self assembling proteins for producing extended materials

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Self-assembling fusion proteins and nucleic acids encoding the same are provided. The subject fusion proteins include a first dimer forming oligomerization domain and a second tetramer forming oligomerization domain rigidly linked to each other. Also provided are regular structures made up of a plurality of self-assembled fusion proteins of the subject invention, and methods for producing the same. The subject fusion proteins find use in the preparation of self-assembled nanostructures, e.g., two-dimensional layers and three-dimensional networks, which structures find use in a variety of different applications.
Yeates, Todd O. (Agoura Hills, CA), Padilla, Jennifer (Pasadena, CA), Yoshida, Stephanie (Seattle, WA), Colovos, Chris (Thousand Oaks, CA)
10/ 815,543
March 31, 2004
ACKNOWLEDGMENT OF GOVERNMENT SUPPORT [0002] This invention was made with Government support under Grant No. GM31299 awarded by the National Institute of Health; Grant No. MCB-0103549 from the National Science Foundation and Grant No. DE-FG03-87ER60615 awared by the Department of Energy. The Government has certain rights in this invention.