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Multiplexed diagnostic platform for point-of care pathogen detection

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Lawrence Livermore National Laboratory - Visit the Industrial Partnerships Office Website
The invention provides a system for high-throughput multiplex analysis of target samples. A sample and reagent delivery unit is operatively connected to a thermal cycler for amplification of target nucleic acids. Microspheres are hybridized to the resulting amplicons in the thermal cycler. A flow cytometer is operatively connected to the thermal cycler or optionally a bead trap for washing the microspheres.
McBride, Mary T. (Brentwood, CA), Hindson, Benjamin J. (Livermore, CA), Brown, Steve B. (Livermore, CA)
The Regents of the University of California
11/ 335,074
January 18, 2006
[0001] The United States Government has rights in this invention pursuant to Contract No. W-7405-ENG-48 between the U.S. Department of Energy and the University of California, for the operation of Lawrence Livermore National Laboratory.