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High stability, high activity coatings and processes for using same

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Pacific Northwest National Laboratory - Visit the Technology Commercialization Program Website
The present invention relates to a high stability, high activity coating and processes for using the same. The coating has high biocatalytic activity and stability useful on surface of various materials and fibers, e.g., polymer fibers applicable in heterogeneous environments. In one illustrative approach, enzyme "seed" are covalently attached to polymer nanofibers followed by treatment with a reagent that crosslinks additional enzyme molecules and aggregates to the seed enzymes improving enzyme (biocatalytic) activity due to increased enzyme loading and enzyme stability. The coating has potential new applications in such areas as bioconversion, bioremediation, biosensors, and biofuel cells.
Kim, Jungbae (Richland, WA), Kwak, Ja Hun (Richland, WA), Grate, Jay W. (West Richland, WA)
Battelle Memorial Institute (Richland WA)
11/ 251,527
September 30, 2005
[0001] This invention was made with Government support under Contract DE-AC05-76RLO1830 awarded by the U.S. Department of Energy. The Government has certain rights in the invention.