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United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Nanocages are formed by etching nancubes. The nanocubes are added to an aqueous system having an amphiphilic lipid dissolved in an organic solvent (e.g. a hydrophobic alcohol) to form reverse micelles. As the water evaporates the micelles shrink as etching of the flat surface of the nanocubes occurs. In this fashion hollow nanocages are produced. In one embodiment, the nanocage is covalently attached to a polymer shell (e.g. a dextran shell).
Matsui, Hiroshi (Glen Rock, NJ), Wei, Zengyan (Corona, NY), Fang, Justin (New York, NY)
15/ 477,601
April 3, 2017
STATEMENT OF FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT [0002] This invention was made with government support under contract number DE-FG-02-01ER45935 awarded by the U.S. Department of Energy. Support was also provided under contract number MD007599 awarded by the National Institute on Minority Health and Health Disparities (National Institute of Health). The government has certain rights in the invention.