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United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Methods of producing and isolating .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.13N, .sup.52Mn, or .sup.44Sc and solution targets for use in the methods are disclosed. The methods of producing .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.13N, .sup.52Mn, or .sup.44Sc include irradiating a closed target system with a proton beam. The closed target system can include a solution target. The methods of producing isolated .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61CU, .sup.99mTC, .sup.45-Ti, .sup.52Mn, or .sup.44Sc by ion exchange chromatography. An example solution target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window.
DeGRADO, Timothy R. (Rochester, MN), PANDEY, Mukesh K. (Rochester, MN), BYRNE, John (Boston, MA)
15/ 311,052
May 15, 2015
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH [0002] This invention was made with government support under SC0008947 awarded by the Department of Energy. The government has certain rights in the invention.