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Outcome prediction and risk classification in childhood leukemia

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
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Genes and gene expression profiles useful for predicting outcome, risk classification, cytogenetics and/or etiology in pediatric acute lymphoblastic leukemia (ALL). OPAL1 is a novel gene associated with outcome and, along with other newly identified genes, represent a novel therapeutic targets.
Willman, Cheryl L. (Albuquerque, NM), Helman, Paul (Albuquerque, NM), Veroff, Robert (Albuquerque, NM), Mosquera-Caro, Monica (Albuquerque, NM), Davidson, George S. (Albuquerque, NM), Martin, Shawn B. (Albuquerque, NM), Atlas, Susan R. (Albuquerque, NM), Andries, Erik (Rio Rancho, NM), Kang, Huining (Albuquerque, NM), Shuster, Jonathan J. (Gainesville, FL), Wang, Xuefei (Albuquerque, NM), Harvey, Richard C. (Placitas, NM), Haaland, David M. (Albuquerque, NM), Potter, Jeffrey W. (Albuquerque, NM)
10/ 729,895
December 5, 2003
STATEMENT OF GOVERNMENT RIGHTS [0002] This invention was made with government support under a grant from the National Institutes of Health (National Cancer Institute), Grant No. NIH NCI U01 CA88361; and under a contract from the Department of Energy, Contract No. DE-AC04-94AL85000. The U.S. Government has certain rights in this invention.