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Nucleic acid encoding DS-CAM proteins and products related thereto

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
In accordance with the present invention, there are provided novel Down Syndrome-Cell Adhesion Molecule (DS-CAM) proteins. Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention DS-CAM proteins can be employed in a variety of ways, for example, for the production of anti-DS-CAM antibodies thereto, in therapeutic compositions and methods employing such proteins and/or antibodies. DS-CAM proteins are also useful in bioassays to identify agonists and antagonists thereto.
Korenberg, Julie R. (Los Angeles, CA)
Cedars-Sinai Medical Center
11/ 134,587
May 20, 2005
ACKNOWLEDGMENT [0002] This invention was made with Government support under Grant Numbers HL50025 and HD17449 awarded by the National Institutes of Health and DE-FG03-92ER61402 awarded by the Department of Energy. The Government has certain rights in this invention.