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System and method for electrokinetic trapping and concentration enrichment of analytes in a microfluidic channel

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
According to one embodiment of the invention, a method for chemical analysis includes providing a device having a drain region, a source region, and a gate region disposed therebetween, associating a buffer solution with the drain region and the source region, causing a potential difference between the drain region and the source region until a stable current is reached, replacing the buffer solution in the source region with a solution containing an analyte, and applying a negative potential to the source region to create a forward bias.
Crooks, Richard M. (College Station, TX), Ito, Takashi (Manhattan, KS), Sun, Li (College Station, TX), Dai, Jinhau (Lansing, MI), Dhopeshwarkar, Rahul R. (College Station, TX)
10/ 916,320
August 11, 2004
[0002] This invention was made with Government support from the Department of Energy, Basic Energy Sciences, Contract No. DE-PG03-01HER15247. The Government may have certain rights in this invention.