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Antisense and pretargeting optical imaging

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
The present invention relates, in part, to detectably labeled oligomer duplexes and their use in optical imaging, including, in vivo optical imaging. The invention includes methods of optical imaging including in vivo pretargeting methods and in vivo antisense optical imaging methods.
Hnatowich, Don (Brookline, MA), Nakamura, Kayoko (Tokyo, JP), Wang, Yi (Worcester, MA), Liu, Xinrong (Worcester, MA), He, Jiang (San Mateo, CA), Zhang, Surong (Shrewsbury, MA), Rusckowski, Mary (Southborough, MA)
University of Massachusetts (Boston MA)
12/ 009,452
January 18, 2008
GOVERNMENT SUPPORT [0002] This invention was made in part with government support under grant number RO1 CA94994 from the National Institutes of Health (NIH) and DE-FG02-03ER63602 from the Department of Energy. The U.S. government has certain rights in this invention.