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Growth of large patterned arrays of neurons on CCD chips using plasma deposition methods

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
Neuroelectronic devices are disclosed which use charge-coupled detector array devices to stimulate, monitor and record neural network activity and response. The method and apparatus described herein uses vacuum-arc-plasma based methods of surface modification as a tool for forming large patterned neuronal arrays on substrates. The basic device features a charge coupled detector device array (CCD) having a thin protective film over the CCD, a thin patterned film to promote neuron growth, and an insulator. Methods for stimulating and monitoring stimulated and spontaneous electrical activity in individual neurons of the array can be carried out by the apparatus described.
Brown, Ian G. (Berkeley, CA), Blakely, Eleanor A. (Oakland, CA), Monteiro, Othon R. (Oakland, CA), Galvin, James E. (Emeryville, CA), Bjornstad, Kathleen A. (Oakland, CA)
The Regents of the University of California (1111 Franklin Street 12th Floor Oakland CA 94607-5200)
10/ 809,269
March 24, 2004
[0002] This invention was made during work supported by U.S. Department of Energy under Contract No. DE-AC03-76SF00098. The government has certain rights in this invention.