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Method for image reconstruction of moving radionuclide source distribution

United States Patent Application

*** PATENT GRANTED ***
20100316275
8,335,363
A1
View the Complete Application at the US Patent & Trademark Office
Thomas Jefferson National Accelerator Facility - Visit the Technology Review Committee Website
A method for image reconstruction of moving radionuclide distributions. Its particular embodiment is for single photon emission computed tomography (SPECT) imaging of awake animals, though its techniques are general enough to be applied to other moving radionuclide distributions as well. The invention eliminates motion and blurring artifacts for image reconstructions of moving source distributions. This opens new avenues in the area of small animal brain imaging with radiotracers, which can now be performed without the perturbing influences of anesthesia or physical restraint on the biological system.
Stolin, Alexander V. (Newport News, VA), McKisson, John E. (Hampton, VA), Lee, Seung Joon (Knoxville, TN), Smith, Mark Frederick (Catonsville, MD)
Jefferson Science Associates, LLC
12/ 456,372
June 16, 2009
[0001] The United States of America may have certain rights to this invention under Management and Operating Contract DE-AC05-060R23177 from the United States Department of Energy.