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Plant cell wall loosening activity of group 2/3 allergens of grass pollen

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
The present invention provides nucleic acids and polypeptide sequences for a novel class of expansin-related proteins, designated group 2/3 allergen, which comprise the group 2 and group 3 allergens from grass, a purified group 3 allergen Lol p 3, and method of using the nucleic acids sequences and proteins of the invention. Group 2/3 allergens of the invention are significant wall-loosening agents. They are capable of altering cell wall properties, which may effect growth, flexibility, and mechanical strength in tissues in which they are expressed.
Li, Lian-Chao (State College, PA), Cosgrove, Daniel J. (Pennsylvania Furnace, PA)
10/ 628,296
July 28, 2003
[0002] This work is supported by the Department of Energy pursuant to Grant No. DE-FG02-84ER13179. Accordingly, the U.S. Government may have certain rights in the invention.