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Prevention of addiction in pain management

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Brookhaven National Laboratory - Visit the Office of Technology Commercialization and Partnerships Website
The present invention provides a composition for treating pain. The composition includes a pharmaceutically acceptable analgesic with addictive liability and a GABAergic agent, such as gamma vinyl GABA (GVG) or topiramate, which is effective in reducing or eliminating the addictive liability of the analgesic without interfering with its pain relieving properties.
Dewey, Stephen L. (Manorville, NY), Brodie, Jonathan D. (Cos Cob, CT), Ashby, Charles R. (Miller Place, NY)
10/ 335,800
January 2, 2003
[0002] This invention was made with Government support under contract number DE-AC 02-98CH10886, awarded by the U.S. Department of Energy. The Government has certain rights in the invention.