Prevention and Treatment of Fouled Medical Device Surfaces
11-G00256_ID2324.pdf (655 KB)
fouling from infectious bacteria forming biofilms on the device. Relying on
antibiotics to treat infection is increasingly problematic, as antibiotic-resistant
strains are now common. In addition, treating biofilms with antibiotics is generally
ineffective due to the inability of the antibiotic to penetrate the biofilm.
BenefitsIn this technology, fouling is avoided by applying stimuli to the material structure in order to yield an increase or decrease in the temperature of the energetically activated nanostructure. The invention works by modifying the chemical and/or mechanical properties of the base material so that bacterial fouling is obstructed. It is also possible to provide a coated structure with an activated nanostructure.
•Helps avoid costly removal and reinsertion of medical implants and antibiotic therapy
•Disrupts the formation of biofilms, which are resistant to antibiotic therapy
•Minimizes damage to tissue adjacent to the implant while destroying microbes and pathogensApplications and Industries•Devices inserted into individuals for medical tests, drug treatments, cosmetic applications, and long-term corrective measures
•Vascular catheters in kidney dialysis
•Catheters to introduce medications, nourishment, and drugs over an extended time
•Shunts to move liquid from one part of the body to another, such as the ventriculoperitoneal shunt used to relieve intracranial pressureMore InformationMitchel J. Doktycz, David P. Allison, Charles F. Barnett, and Scott T. Retterer. Active Materials for Prevention and Treatment of Fouled Surfaces, U. S. Patent Application No. 61/483,133, filed May 6, 2011.Technology Status
|Technology ID||Development Stage||Availability||Published||Last Updated|
|UT-B ID 200902324||Development||Available||11/21/2011||10/27/2011|