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A SERS Method for Handheld Portable Raman

Sandia National Laboratories

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Technology Marketing Summary

Sandia National Laboratories (SNL) has made an initial investment in the research and development of Surface Enhanced Raman hardware capable of being integrated into a handheld Raman system, which can provide detection for certain analytes down to ppm levels.  The developed method concentrates vapor phase analytes for subsequent deposition onto a functionalized SERS surface.   SNL is seeking commercial partners who are interested in investing in the further development of this technology to create a product that could be deployed by the industrial, first responder and military communities. 


SNL is seeking a Cooperative Research and Development Agreement (CRADA) with an industrial partner with proven experience in the design, development, and deployment of handheld Raman spectrometers. The objective of this partnership would be the joint development of a drop-in SERS based sampling unit, composed of a SERS sampling vial and a sample pre-concentration system.  Collaborators will work with SNL on the integration and testing of the SERS system with existing handheld Raman instrumentation.  This will involve not only hardware development, but also expansion of the library functions to include SERS analysis of pertinent materials.  The desired outcome of the collaboration will be commercialization/deployment of the technology through refined product design, optimization, and quality assurance. Qualified partners will contribute resources, including funds-in support to SNL and in-kind support in the form of laboratory staff and instrumentation.  Qualified partners will have the option to obtain, up to and including, an exclusive license to the intellectual property in a pre-defined field of use for reasonable compensation. 

More Information

Interested parties are invited to respond. For more information visit:

Technology Status
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To: Kathy Alam<>