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Boronated porhyrins and methods for their use

United States Patent

5,877,165
March 2, 1999
View the Complete Patent at the US Patent & Trademark Office
Brookhaven National Laboratory - Visit the Office of Technology Commercialization and Partnerships Website
The present invention covers boronated porphyrins containing multiple carborane cages which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies such as boron neutron capture therapy and photodynamic therapy.
Miura; Michiko (Hampton Bays, NY), Shelnutt; John A. (Tijeras, NM), Slatkin; Daniel N. (Southhold, NY)
Brookhaven Science Associates (Upton, NY)
08/ 874,548
June 13, 1997
This invention was made with Government support under contract number DE-AC02-76CH00016, awarded by the U.S. Department of Energy. The Government has certain rights in the invention.