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Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions

United States Patent

5,853,695
December 29, 1998
View the Complete Patent at the US Patent & Trademark Office
Brookhaven National Laboratory - Visit the Office of Technology Commercialization and Partnerships Website
The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a method for simultaneous palliation of bone pain and radiotherapy in cancer patients using compositions containing Sn-117m chelates. The invention also provides a method for palliating bone pain in cancer patients using Sn-117m-containing compositions and monitoring patient status by imaging the distribution of the Sn-117m in the patients. Also provided are pharmaceutically acceptable compositions containing Sn-117m chelate complexes for the palliation of bone pain in cancer patients.
Srivastava; Suresh C. (Setauket, NY), Meinken; George E. (Middle Island, NY), Mausner; Leonard F. (Stony Brook, NY), Atkins; Harold L. (Setauket, NY)
Brookhaven Science Associates LLC (Upton, NY)
08/ 743,287
November 4, 1996
The U.S. Government has rights to this invention pursuant to Contract No. DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities, Inc.