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Cell-targeted lytic pore-forming agents

United States Patent

5,817,771
October 6, 1998
View the Complete Patent at the US Patent & Trademark Office
A chimeric compound that contains a cell-specific ligand linked to a pore-forming agent capable of lysing a cell.
Bayley; Hagen (Grafton, MA), Walker; Barbara J. (Auburn, MA)
Worcester Foundation for Experimental Biology (Shrewsbury, MA)
08/ 364,429
December 27, 1994
STATEMENT AS TO FEDERALLY SPONSORED RESEARCH This invention was made with Government support under DE-FG02-90ER20018 awarded by the Department of Energy, co-sponsored by the Division of Energy Biosciences and the Division of Materials Sciences. The Government has certain rights in the invention.