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Biomarkers of cell senescence

United States Patent

5,795,728
August 18, 1998
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention provides a biomarker system for the in vivo and in vitro assessment of cell senescence. In the method of the present invention, .beta.-galactosidase activity is utilized as a means by which cell senescence may be assessed either in vitro cell cultures or in vivo.
Dimri; Goberdhan P. (Simli U.P., IN), Campisi; Judith (Berkeley, CA), Peacocke; Monica (Newton, MA)
The Regents of the University of California (Oakland, CA)
08/ 479,082
June 7, 1995
GOVERNMENT RIGHTS This invention was made with Government support under Contract No. DE-AC03-76SF00098, between the U.S. Department of Energy and the University of California for the operation of Lawrence Berkeley Laboratory. The Government has certain rights in this invention.