An inactive pore-forming agent which is activated to lytic function by a condition such as pH, light, heat, reducing potential, or metal ion concentration, or substance such as a protease, at the surface of a cell.
STATEMENT AS TO FEDERALLY SPONSORED RESEARCH
This invention was made with Government support under Grant No. DE-FG02-90ER20018 awarded by the Department of Energy, co-sponsored by the Division of Energy Biosciences and the Division of Materials Sciences, Grant No. N00014-93-1-0962 awarded by the Office of Naval Research, and Grant No. R01 NS26760 awarded by the National Institutes of Health. The Government has certain rights in the invention.