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DNA complexes with dyes designed for energy transfer as fluorescent markers

United States Patent

5,767,267
June 16, 1998
View the Complete Patent at the US Patent & Trademark Office
Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated.
Glazer; Alexander M. (Orinde, CA), Benson; Scott C. (Albany, CA)
The Regents of the University of California (Berkeley, CA)
08/ 771,443
December 20, 1996
CROSS-REFERENCE TO GOVERNMENT GRANT This invention was made with Government support under Grant Contract No. DE-FG-91ER61125 awarded by the Department of Energy. The Government has certain rights in this invention.